If you're having trouble with the patcher or don't trust it, you can also use this guide(though you need visual studio and editbin), just replace python with pol:
https://gisgeek.blogspot.com/2012/01/set-32bit-executable-largeaddressaware.html
Other things to check:
-Make sure POL and FFXI aren't running, you can't edit the file while it's in use.
-Make sure you run as admin(pol.exe is likely in program files and newer windows are super picky about anything in there).
-Not sure what in there would trigger virus detection, windows defender didn't give me any trouble, but if your virus software doesn't like it then whitelist it.
If a ffxi update replaces pol.exe or an ashita/windower/server update replaces your bootloader, you'll have to patch it again.